CRISPR/Cas Biosensing Systems - Opportunities and Challenges in Diagnostic Applications

Join Professor Guozhen Liu in a 37-minute webinar exploring the evolving landscape of CRISPR/Cas systems in diagnostic applications. Discover how these systems have expanded beyond gene editing to become powerful biosensing tools with exceptional sensitivity and specificity. Learn about groundbreaking developments in CRISPR/Cas-based biosensors, including SHERLOCK, SHERLOCKv2, DETECTR, and HOLMES systems. Explore recent advances in detecting non-nucleic acid targets like small molecules, proteins, exosomes, and metal ions. Examine various signal read-out methods including fluorescence, colorimetric, electrochemiluminescence, electrochemical, and electrical modalities. Understand the potential of multiplexed testing and the integration with lateral flow devices for sensitive pathogen and virus detection. Benefit from the expertise of Professor Liu, an accomplished researcher in biomedical engineering with extensive experience in both academic and industrial settings, particularly in developing point-of-care diagnostics and medical devices for chronic diseases.