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YouTube

CRISPR-Based Assays: Understanding Errors and Specificity in Molecular Diagnostics

Labroots via YouTube

Overview

Join Stanford Professor Juan G. Santiago in this 31-minute webinar exploring the critical analysis of CRISPR-based molecular diagnostics and their potential in medical applications. Discover why most CRISPR enzyme kinetics studies show inconsistent data that violate basic mass conservation and rate laws, and learn about the challenges in reconciling reported limits of detection with CRISPR kinetic rates. Explore groundbreaking research quantifying various CRISPR-Cas systems' kinetics and their fundamental relationship to assay detection limits, while examining CRISPR's remarkable specificity for detecting small mutations, including single-nucleotide polymorphisms. Gain insights into ongoing research leveraging CRISPR's specificity for cancer detection, presented by an accomplished researcher who holds multiple fellowships and has contributed significantly to microsystems development for biochemical analysis and molecular diagnostics.

Syllabus

Reports of CRISPR-Based Assays Exhibit Gross Errors but CRISPR Offers High Specificity

Taught by

Labroots

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