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XuetangX

Biochemistry and Molecular Biology

Huazhong University of Science and Technology via XuetangX

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Overview

Biochemisty and Molecular Biology is a subject studying the essence of life at molecular level. It has an extensive connection and crosstalk with the subject of physiology, pharmacology, pathology, immunology. Furthermore, it has a close association with clinical medicine and help to elucidate clinical pathogenesis at molecular level and solve clinical problem on disease prevention, diagnosis and treatment. In addition, the experimental technology of Biochemistry and Molecular Biology is an important part of natural science. The progress of Biochemistry and Molecular Biology theory and experimental technology plays an important role in the development of life science.

Biochemistry is an important basic course of medicine. Through the study of this course, students are required to master the basic theory of Biochemistry and Molecular Biology including structure and function of biological macromolecules, metabolism and regulation of metabolism of organisms, transfer of genetic information and special topics on Molecular Medicine. In addition, students are required to master basic experimental skills and know new developments of the subject.


Syllabus

  • Introduction
    • 1 The Structure and Function of Proteins
      • 1.1 The molecular composition of proteins
      • 1.2 The molecular structure of proteins
      • 1.3 The relationship between structure and function of proteins
      • 1.4 The physical and chemical properties of amino acids and proteins
    • 2 The Structure and Function of Nucleic acid
      • 2.1 The chemical composition of nucleic acid
      • 2.2 The structure and function of DNA
      • 2.3 The structure and function of RNA
      • 2.4 The physical and chemical properties of nucleic acid
    • 3 Enzymes and the Enzymatic Reaction
      • 3.1 The molecular structure and function of enzymes
      • 3.2 The working principle of enzymes
      • 3.3 The kinetics of enzyme catalyzed reactions
      • 3.4 The regulation of enzymes
    • 4 Vitamins
      • 5 Metabolism of Carbonhydrates
        • 5.1 Overview of Metabolism of Carbonhydrates
        • 5.2 Anaerobic Oxidation of Carbohydrates
        • 5.3 Aerobic Oxidation of Carbohydrates
        • 5.4 Pentose Phosphate Pathway and Favism
        • 5.5 Glycogenesis and Glydogenolysis
        • 5.6 Gluconeogenesis and Lactic Acid Cycle
        • 5.7 Blood Glucose and Its Regulation
      • 6 Metabolism of Lipids
        • 6.1 The Chemistry and Function of Lipids
        • 6.2 The Digestion and Absorption of Lipids
        • 6.3 Metabolism of Triglyceride
        • 6.4 Metabolism of Phospholipids
        • 6.5 Metabolism of Cholesterol
        • 6.6 Plasma Lipoproteins and its Metabolism
      • 7 Biological Oxidation
        • 7.1 Biological Oxidation
        • 7.2 Respiratory Chain
        • 7.3 Oxidative Phosphorylation
        • 7.4 Other Oxidative and Antioxidative Systems
      • 8 Metabolism of Amino acids
        • 8.1 Proteins Function and Nutrition
        • 8.2 Proteins Digestion, Absorption and Putrefaction
        • 8.3 The General Metabolism of Amino acids
        • 8.4 Metabolism of Ammonia
        • 8.5 Metabolism of Individual Amino acid
      • 9 Metabolism of Nucleotides
        • 9.1 Metabolism of Purine Nucleotides
        • 9.2 Metabolism of Pyrimidine Nucleotides
        • 9.3 Anti-metabolites and Anti-tumor drugs
      • 10 Integration and Regulation of Metabolism
        • 10.1 Integration of Metabolism
        • 10.2 Metabolism Characteristics of Important Extrahepatic Organs
        • 10.3 Regulation of Metabolism
      • 11 The Liver Biochemistry
        • 11.1 Biotransformation
        • 11.2 Metabolism of Bile acids
      • 12 The Blood biochemistry
        • 12.1 Metabolism of Erythrocytes
        • 12.2 Bile Pigment Metabolism and Jaundice
      • 13 Eukaryotic Gene and Genome
        • 13.1 Structure and Function of Eukaryotic Genes
        • 13.2 Characteristics of Eukaryotic Genomes
      • 14 DNA Synthesis
        • 14.1 DNA Replication Features and Enzymology
        • 14.2 DNA Replication Process
        • 14.3 Reverse Transcription
      • 15 DNA Damage and Repair
        • 15.1 DNA Damage and Repair
      • 16 RNA Synthesis
        • 16.1 Transcription
        • 16.2 Prokaryote Transcription
        • 16.3 Eukaryote Transcription
        • 16.4 Post-transcription Process
      • 17 Protein Synthesis
        • 17.1 Protein Biosynthesis System
        • 17.2 Protein Biosynthesis Process
      • 18 The Regulation of Gene Expression
        • 18.1 Basic Concepts and Characteristics of Gene Expression Regulation
        • 18.2 Prokaryote Gene Expression Regulation
        • 18.3 Eukaryote Gene Expression Regulation
      • 19 Signal Transduction
        • 19.1 Summary of Cell Signal Transduction
        • 19.2 Intracellular Signal Transduction Molecules
        • 19.3 Signal Transduction Pathways
      • 20 Common Molecular Biology Techniques
        • 20.1 Nucleic acid Hybridization and Blotting Technique
        • 20.2 Principle and Application of PCR Technique
      • 21 Recombinant DNA Technology
        • 21.1 Enzymes and Vectors of Recombinant DNA Technology
        • 21.2 Basic Principles of Recombinant DNA Technology
      • 22 Oncogene and Tumor Suppressor Gene
        • 22.1 Oncogene and Tumor
        • 22.2 Tumor Suppressor Gene

      Taught by

      Sun Jun, Shi Anbing, YUAN PIng, GUO Jiali, and

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