Novel Tools for Drug Discovery in Neurodegenerative Diseases

Explore novel tools for drug discovery in neurodegenerative diseases in this 27-minute webinar presented by Dr. Jacob McPhail, a biochemist specializing in protein complexes. Gain insights into Alzheimer's and Parkinson's diseases, focusing on the abnormal protein aggregates that characterize these disorders. Learn about innovative methods for generating active neurotoxic protein aggregates in vitro, including fibrils of pyroglutamate Aβ and tau dGAE fragment. Discover how these molecular tools can expand research possibilities and facilitate drug discovery efforts for neurodegenerative diseases. Understand the potential of co-polymer alpha-synuclein and tau fibrils in advancing our understanding of disease pathology. Delve into the latest advancements in creating disease models that effectively mimic in vivo pathology, crucial for accelerating Alzheimer's and Parkinson's drug discovery research.