Mechanisms and Applications of DNA Methylation and Gene Silencing in Plants

Explore the intricate world of DNA methylation and gene silencing in plants through this 46-minute lecture by Prof. Steve Jacobsen from the University of California, Los Angeles. Delve into the elaborate systems plants have developed for establishing and maintaining DNA methylation, including self-reinforcing loops that enable the heritability of DNA methylation differences through cell division. Discover the components and mechanisms involved in reading and interpreting DNA methylation, and learn how it can lead to gene silencing or, in some cases, gene activation. Gain insights into the development of CRISPR-based tools for precise targeting of DNA methylation changes, with potential applications in basic plant research and crop improvement. This seminar, part of the Monthly Seminar on Physical Genomics series, offers a comprehensive look at cutting-edge research in plant genomics and its practical implications.