Center for Physical Genomics and Engineering Courses

Investigating Gene Activation Dynamics in Human Polycomb Chromatin with Synthetic Reader-Effectors

Explore gene activation dynamics in human polycomb chromatin using synthetic reader-effectors. Gain insights from Dr. Karmella Haynes' research on applying chromatin properties to engineer proteins controlling cell development.

• YouTube
• 36 minutes
• On-Demand
• Free Video

Modeling of Nucleosome Clustering in Euchromatin Resulting from Reader Protein Interactions

Explore nucleosome clustering in euchromatin through modeling interactions between reader proteins. Gain insights into chromosomal organization and dynamics from the Spakowitz lab's research.

• YouTube
• 25 minutes
• On-Demand
• Free Video

Ultraresolution Imaging Through Deep Tissue and Information-Based Theoretical Resolution Limit

Explore ultraresolution imaging techniques for deep tissue and discover a novel information-based theoretical resolution limit in this cutting-edge biomedical engineering presentation.

• YouTube
• 31 minutes
• On-Demand
• Free Video

Super-Resolution Imaging of Chromatin Structure and Dynamics in Health and Disease

Explore super-resolution imaging techniques for chromatin structure and dynamics in health and disease with Dr. Melike Lakadamyali's cutting-edge research and insights.

• YouTube
• 32 minutes
• On-Demand
• Free Video

Gene Regulation in Cellular Senescence

Explore gene regulation in cellular senescence with Prof. Masashi Narita, uncovering key insights on epigenetic aspects and senescence-associated heterochromatic foci (SAHFs).

• YouTube
• 35 minutes
• On-Demand
• Free Video

3D Chromatin Rewiring During Melanoma Phenotypic Transition

Explore 3D chromatin architecture's role in melanoma phenotype transitions. Discover how MITF and mechanical factors influence chromatin folding and gene expression in cancer progression.

• YouTube
• 1 hour 2 minutes
• On-Demand
• Free Video

Fossils of Ancient Chromosomes

Explore ancient genome reconstruction using Hi-C technology. Discover how innovative DNA sequencing methods unveil prehistoric chromosomal structures, revolutionizing paleogenomics and evolutionary biology.

• YouTube
• 53 minutes
• On-Demand
• Free Video

The X Factor: Unveiling the Secrets of the X-Chromosome with Data-Driven 3D Modeling

Explore X-chromosome structure and function through data-driven 3D modeling, uncovering insights into sex-specific diseases and potential targeted therapies. Learn about expanding techniques to entire genomes.

• YouTube
• 1 hour 3 minutes
• On-Demand
• Free Video

Towards an Understanding of Chromatin Remodeler Function in Development at Single-Cell Resolution

Explore chromatin regulators' role in mammalian development and human disorders through single-cell analysis of mouse knockouts, uncovering developmental impacts and gene networks.

• YouTube
• 52 minutes
• On-Demand
• Free Video

Genomics and Transcriptomics of Heart Disease

Explore genomics and transcriptomics in heart disease, focusing on regulatory elements, SNPs, and gene networks to enhance understanding of cardiovascular pathogenesis and therapy.

• YouTube
• 49 minutes
• On-Demand
• Free Video

A Day in the Life of a Data Scientist

Explore the daily realities of data science careers and discover the innovative collaboration between WWT and Northwestern's CPGE in this insightful seminar.

• YouTube
• 1 hour 10 minutes
• On-Demand
• Free Video

Gene Structure Heterogeneity and Loop Extrusion Drive Transcriptional Noise in Human Cells

Explore how gene structure diversity and loop extrusion mechanisms influence transcriptional variability in human cells, impacting phenotypic variation within cell populations.

• YouTube
• 1 hour 3 minutes
• On-Demand
• Free Video

Physical Genomics Training Program Research Showcase

Explore cutting-edge research in physical genomics, including genome organization mapping, nanoparticle-based cancer treatment, and chromatin organization in transcription.

• YouTube
• 56 minutes
• On-Demand
• Free Video

Probing Principles of Genome Organization and Function

Explore innovative genomics technologies for understanding gene regulation and chromatin organization in mammalian cells. Discover approaches to alter genomic structure and study its impact.

• YouTube
• 54 minutes
• On-Demand
• Free Video

RNA Methylation in Chromatin Regulation

Explore RNA methylation's role in chromatin regulation and gene expression. Discover groundbreaking findings on reversible RNA modifications and their impact on biological processes.

• YouTube
• 33 minutes
• On-Demand
• Free Video