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Explore how to enhance Matplotlib's performance using the GR framework in this EuroPython conference talk. Learn about designing high-performance visualization applications for Linux, OS X, and Windows by combining Matplotlib with GR, a powerful graphics library. Discover techniques to improve responsiveness and frame rates in animated visualizations, enabling Matplotlib's use in real-time environments such as signal processing. Examine concrete examples demonstrating GR framework's benefits as a companion module for Matplotlib in both Python and Julia. Gain insights into GR's interoperability with graphical user interfaces (Qt/PySide) and OpenGL, opening up new possibilities for existing Matplotlib applications. Witness the system's performance capabilities through demanding live applications and explore how this combination can overcome Python's limitations when processing large amounts of data or visualizing three-dimensional scenes.