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Homology Modeling for Beginners - COVID-19 NP Protein Modeling with Modeller

Bioinformatics With BB via YouTube

Overview

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Learn the fundamentals of homology modeling in this 25-minute tutorial video focused on COVID-19 NP protein modeling using the Modeller tool. Explore the process of constructing atomic-resolution models of target proteins from amino acid sequences and experimental 3D structures of related homologous proteins. Gain hands-on experience with the Modeller software, understand the basics of sequence alignment, and discover various homology modeling tools and web servers. Follow along with practical examples, including working with PIR files and using Verify3D for model validation. Dive into the essential concepts and techniques of protein structure prediction in bioinformatics.

Syllabus

Introduction
Protein Sequence
Crystalline Structure
Manual Creation
Align Sequence
Alignment Language
Sequence Alignment

Taught by

Bioinformatics With BB

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