Broad Institute Courses

Sparsity, Epistasis, and Models of Fitness Functions - Leveraging Interactions in Protein Function Prediction

Explore sparsity in epistatic interactions to enhance fitness function modeling. Learn about Walsh-Hadamard transform, Graph Fourier transforms, and Epistatic Net for improved protein function prediction.

• YouTube
• 1 hour 37 minutes
• On-Demand
• Free Video

Contrastive Models for Case-Control Changes in Sequencing - Models, Inference and Algorithms

Explore contrastive latent variable models for analyzing differential expression in sequencing data, enhancing case-control comparisons in transcriptomics with novel approaches to capture condition-specific variations.

• YouTube
• 1 hour 8 minutes
• On-Demand
• Free Video

Harmonization of Deeply Sequenced Genomes - MPG Primer 2023

Explore genome harmonization techniques for deeply sequenced data, covering quality control, structural variants, and PCA analysis using cloud computing.

• YouTube
• 37 minutes
• On-Demand
• Free Video

MPG Primer: suSIEx - Medical and Population Genetics 2023

Explore suSIEx, a cutting-edge method for analyzing genetic data in medical and population genetics. Learn its principles, applications, and potential impact on understanding complex traits and diseases.

• YouTube
• 39 minutes
• On-Demand
• Free Video

Thoughtful Use of Population Descriptors in Genomic Research - Equity in Biomedicine Seminar

Explore ethical considerations in using population descriptors for genomic research. Learn from experts about the importance of thoughtful group categorization in science and society.

• YouTube
• 57 minutes
• On-Demand
• Free Video

Mostly Natural Sequencing-by-Synthesis for scRNA-seq Using Ultima Sequencing - 2023 MPG Primer

Explore natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing. Learn about experiment design, data quality, analysis techniques, and biological insights in single-cell genomics.

• YouTube
• 44 minutes
• On-Demand
• Free Video

Emerging Scientific Visionaries Tackle Critical Health Challenges - BroadIgnite

Explore groundbreaking research by emerging scientists on neurodegenerative diseases, cardiac health, infectious disease diagnosis, and rare genetic disorders.

• YouTube
• 1 hour 2 minutes
• On-Demand
• Free Video

Mass-Spectrometry-Based Proteomics for Biomarker Discovery and pQTL Mapping

Explore mass spectrometry-based proteomics techniques for biomarker discovery and pQTL mapping in this workshop by Lili Niu from the University of Copenhagen.

• YouTube
• 36 minutes
• On-Demand
• Free Video

Integrating Patient Level Multi-omics Data Using Deep Learning Models

Explore deep learning models for integrating patient-level multi-omics data, focusing on supervised and unsupervised approaches for predicting outcomes and uncovering latent representations in genomics.

• YouTube
• 50 minutes
• On-Demand
• Free Video

Deep Learning for Genomic Discovery

Explore deep learning techniques for genomic discovery, focusing on high-resolution assays, footprint shapes, and bias correction methods in neural networks.

• YouTube
• 1 hour 8 minutes
• On-Demand
• Free Video

Mendelian Randomization: Two Decades or 150 Years of Evolution - Lecture

Explore Mendelian randomization's evolution, from its genetic roots to modern applications in epidemiology. Gain insights into its capabilities, limitations, and potential future developments in phenotypic causation research.

• YouTube
• 1 hour 17 minutes
• On-Demand
• Free Video

Copy Number Alterations in Slide-seq Data - MPG Primer 2023

Explore spatial copy number alteration detection in Slide-seq-like spatial transcriptomics data. Learn basic genetics principles related to human populations and disease.

• YouTube
• 55 minutes
• On-Demand
• Free Video

Type 2 Diabetes in Latino Populations - René Salazar Speaker Series 2023

Explore Type 2 diabetes prevalence in Latino populations with Dr. Jose Florez's insightful presentation on genetic and environmental factors.

• YouTube
• 56 minutes
• On-Demand
• Free Video

Individual-level Tissue-Specific Imputed Transcriptomes in Drug Target Prioritization and Disease Risk Prediction

Explore tissue-specific transcriptomes for drug target prioritization and disease risk prediction. Learn about TWAS, co-localization, polygenic risk scores, and phenome-wide scans in genetics research.

• YouTube
• 39 minutes
• On-Demand
• Free Video

Mechanism of a Protein Antibiotic in Bacteriophage Lysis - Broad-MIT Seminar 2023

Explore the mechanism of protein antibiotics through the study of bacteriophage lysis proteins, focusing on Protein E's inhibition of MraY and its implications for novel therapeutic development.

• YouTube
• 1 hour 4 minutes
• On-Demand
• Free Video