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Explore an advanced mathematical lecture on the generalization of the Deligne-Simpson problem to G-connections on P^1 with regular and irregular singularities. Delve into complex reductive groups, rational Cherednik algebras, and the surprising connections between these concepts. Learn about the collaborative research efforts involving Konstantin Jakob, Bezrukavnikov, Boixeda Alvarez, McBreen, and Oblomkov. Gain insights into the solution of this irregular Deligne-Simpson problem and its implications for algebraic geometry and representation theory.