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Explore the mechanisms behind sex differences in disease incidence and progression in this 28-minute webinar presented by Dr. Arthur P. Arnold. Discover how specialized mouse models have revealed non-hormonal origins of sex bias in diseases, challenging the historical view that gonadal hormones were the sole cause of sex differences in tissue phenotypes. Learn about the inherent inequality of XX vs. XY sex chromosomes and their role in contributing to sex-specific disease susceptibility. Gain insights into the latest research on sex chromosome effects and their implications for understanding and treating diseases that show sex-based disparities. After watching, registered Labroots members can earn PACE credits by following the provided instructions.