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Explore the latest updates on Hypermobile Ehlers-Danlos Syndrome (EDS) and hypermobility spectrum disorders (HSD) in this 56-minute video presentation by ERN ReCONNET. Gain insights into the clinical boundaries, molecular genetic diagnostics, and new findings on peripheral microcirculation and skin layers in hypermobile EDS. Learn from expert speakers Dr. Marco Castori, Head of Medical Genetics at Fondazione IRCCS-Casa Sollievo della Sofferenza, and Prof. Alberto Sulli, Associate Professor of Rheumatology at IRCCS Ospedale Policlinico San Martino. Discover the challenges of diagnosing these exclusion disorders, their overlap with other connective tissue disorders, and the importance of molecular testing in confirming diagnoses. Understand the latest research on microvascular fragility and dermal thickness in hypermobile EDS patients.