Unraveling the Roles of Copy Number Variants in Tumorigenesis

Explore the critical role of Copy Number Variants (CNVs) in cancer development through this 47-minute webinar presented by Dr. Xiaolan Fang, Associate Director of cytogenomics and molecular pathology laboratories at Henry Ford Health System. Gain deep insights into how genomic analysis of cancer cells has revealed comprehensive mechanisms of tumorigenesis in human patients, with particular focus on CNVs as crucial biomarkers for early detection, diagnosis, prognosis, and patient care monitoring. Learn about OncoScan CNV assays' robust capabilities in detecting gain, loss, and LOH (Loss of Heterozygosity) patterns that are fundamental to cancer origination, progression, and metastasis. Discover how these assays effectively process highly degraded and low-quality samples commonly found in solid tumor specimens. Examine the development history of this technology and its current research applications in decoding molecular and cytogenetic mechanisms across various representative solid tumor types.