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Explore the fascinating world of strong interaction matter in the universe through this comprehensive theoretical physics colloquium presented by Prof. Achim Schwenk from Technical University of Darmstadt, Germany. Delve into the intricacies of quantum chromodynamics and its role in the formation of hadrons and nuclei that constitute baryonic matter. Examine the latest advances in understanding the densest matter in neutron stars and the highest temperatures reached in compact object mergers. Learn about the progress towards a unified description of all nuclei and matter using effective field theories combined with advanced many-body methods. Discover how neutron-rich nuclei and matter are being investigated through new experimental facilities worldwide and astrophysical observations, including neutron star mergers, heavy neutron star discoveries, and constraints on neutron star radii from NICER. Gain insights into the challenges and developments in predicting strong interaction matter, with a particular focus on equation of state advancements.