Stroke and Dementia: Causes, Treatments, and New Research - Lecture 5/24/23

Explore the intricate connections between stroke and dementia in this comprehensive physician grand rounds presentation. Delve into the complexities of stroke types, including small vessel disease, and examine their relationship to various forms of dementia. Learn about the neurovascular unit and its proposed role in small vessel disease, while gaining insights into clinical definitions and the diverse pathologies causing these conditions. Discover historical perspectives, genetic factors, and the roles of amyloid and tau proteins in dementia. Investigate cutting-edge treatments, including monoclonal antibodies targeting amyloid components. Uncover fascinating new research on stroke and dementia, exploring topics such as age-related differences in stroke recovery, the impact of microbiomes, and potential genetic modifications to address aging. Examine the importance of sleep in glymphatic drainage and its implications for brain health. Finally, consider the role of various RNA types in the neurovascular unit and contemplate the nature of reality in the context of neurological disorders.