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EdgeR and DESeq2, Part 2 - Independent Filtering

StatQuest with Josh Starmer via YouTube

Overview

Explore the differences between edgeR and DESeq2's approaches to filtering genes with low read counts in this informative video. Learn about false positives, histograms, FDR, CPM filtering, sequencing depth, and various CPM cutoffs. Gain insights into the results and their interpretation, as well as the key distinctions between DESeq2 and edgeR methodologies. Discover how to effectively analyze and filter genomic data for more accurate differential expression analysis.

Syllabus

Intro
False positives
Histogram
FDR
Results
Results histogram
CPM
Filtering
Sequencing Depth
Different CPM cutoffs
Differences between DESeq2 edgeR
Summary

Taught by

StatQuest with Josh Starmer

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