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Explore the legacy of Andrei Sakharov and the ongoing importance of defending scientists' human rights in this comprehensive conference talk. Delve into Sakharov's contributions to nuclear fusion, astrophysics, and arms control, as well as his human rights advocacy. Hear from his stepdaughter, Tatiana Yankelevich, and Zafra Lerman, who worked alongside Sakharov to assist persecuted scientists in the USSR. Learn about Sakharov's efforts to mitigate nuclear weapon dangers from Frank von Hippel. Gain insights into current cases of academic freedom suppression and human rights violations against scientists from K.R. Sreenivasan and Alexander Kabanov. Discover ways to deter unjust attacks on physicists and other scientists, with the session chaired by Peter Vorobieff, past chair of the APS Committee on the International Freedom of Scientists.