Understanding GWAS Mechanisms with Transcriptome-Wide Association Studies

Explore the mechanisms of Genome-Wide Association Studies (GWAS) through Transcriptome-Wide Association Studies in this 41-minute tutorial by Sasha Gusev at the Computational Genomics Summer Institute (CGSI) 2022. Delve into cutting-edge research on genetic determinants of chromatin in prostate cancer risk, quantification of genetic effects on disease mediated by gene expression levels, and identification of new susceptibility genes and splice variants in high-grade serous epithelial ovarian cancer. Gain insights from related papers discussing GWAS mechanisms, gene regulation, and their implications in various cancer types.