Explore RNA folding and macrostates in this 1-hour 10-minute lecture by Daniel Aalberts from Williams College. Delve into the definition and visualization of RNA macrostates, groups of microstates separated by free energy barriers. Examine the scaling of base-pair probabilities and more efficient algorithms for computing the ensemble. Discover techniques for optimizing RNA to increase protein over-expression. Learn about the central dogma, RNA structures, Boltzmann factor, and density of states. Gain insights into quantitative predictions of RNA characteristics beyond the minimum free energy microstate.
Overview
Syllabus
Intro
Central dogma
Students
RNA Structures
Boltzmann Factor
Density of States
Optimizing Protein Expression
Macrostates
Taught by
Santa Fe Institute
