Revealing the Mechanism of Genome Organization Using Single-molecule Approaches

Explore the intricate mechanisms of genome organization through single-molecule approaches in this illuminating 29-minute conference talk. Delve into the interdisciplinary aspects of chromatin organization and gene regulation as presented by Mahipal Ganji at the International Centre for Theoretical Sciences. Gain insights into how chromatin, a long polymer containing the genetic code, is arranged in 4D (space and time) and how its epigenetic state and 3D organization influence gene regulation. Discover the latest advances in genomics, high-resolution microscopy, and single-cell level measurements that have revolutionized our understanding of chromatin's complex organization. Learn about the multi-disciplinary approach required to integrate diverse information and comprehend the underlying principles of chromatin structure and function. This talk is part of a broader program that combines pedagogical workshops, hands-on computational modeling sessions, and research presentations, fostering cross-disciplinary collaboration and knowledge exchange in the field of chromatin studies.