Genome Organization and Regulation: Chromatin Domains, Boundaries and Epigenetics

Explore the intricate world of chromatin organization and gene regulation in this 32-minute lecture by Rakesh Mishra from the International Centre for Theoretical Sciences. Delve into the complex 4D arrangement of genetic code within chromatin and discover how epigenetic states and 3D organization influence gene regulation in space and time. Learn about recent advances in genomics, high-resolution microscopy, and single-cell measurements that have revolutionized our understanding of chromatin's underlying principles. Gain insights into the interdisciplinary approach required to integrate diverse information from multiple fields, including experimental observations, physical principles, and data-driven methods. This lecture is part of a comprehensive program on chromatin organization and gene regulation, featuring a pedagogical workshop and scientific meeting that brings together experts from various disciplines to foster cross-disciplinary collaboration and advance our understanding of this crucial biological process.