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Explore groundbreaking research on TRAIL's role in premetastatic niche formation for breast cancer in this 22-minute video. Discover how Dr. Massimiliano Mazzone and Dr. Carla Riera-Domingo uncovered TRAIL's unexpected function as a vascular gatekeeper in the premetastatic niche, offering significant therapeutic potential. Learn about the implications of this novel finding for understanding premetastatic niche formation and its potential impact on cancer treatment. Access the full episode transcript for more details, and delve into the published study in Science Advances to gain deeper insights into this important research highlighted by the European Association for Cancer Research.