Paget's Disease of Bone - Pathophysiology and Clinical Features

Learn about the bone disorder first described by Sir James Paget in 1877 through this medical educational video that explores osteitis deformans, now known as Paget's disease of bone. Understand the complex process of bone remodeling disorders, where increased bone turnover leads to accelerated bone breakdown followed by excessive bone formation, ultimately resulting in bony enlargement and deformity. Discover the pathophysiology and clinical manifestations of this chronic inflammatory bone condition that affects the normal bone remodeling cycle.