Evaluating the Potential Benefits of Embryo Screening Using Polygenic Scores for Multiple Traits

Explore the complex topic of embryo screening using polygenic scores for multiple continuous and disease traits in this 50-minute conference talk by Or Zuk from Hebrew University. Delve into the potential benefits and limitations of this controversial practice, examining recent research and ethical considerations. Gain insights from related papers discussing the utility of polygenic embryo screening, its limited effectiveness for certain traits, and the clinical considerations that warrant further attention. Analyze the whole-genome risk prediction of common diseases in preimplantation embryos and understand the problems associated with using polygenic scores for embryo selection. This talk, presented at the Computational Genomics Summer Institute (CGSI) 2022, offers a comprehensive overview of the current state of research and debates surrounding this cutting-edge topic in reproductive genetics.