Explore practical issues in osteoporosis therapy through this comprehensive grand rounds lecture. Delve into low trauma fractures, hip fracture outcomes, and current treatment failures. Examine proposed solutions, comparing ineffective approaches with promising strategies. Analyze the effects of Denosumab on bone density and its performance against alendronate. Investigate the implications of stopping bisphosphonate treatment and the concept of consolidation therapy. Gain valuable insights into subtrochanteric fractures and the management of Denosumab discontinuation. Learn essential take-home points for improving osteoporosis care and fracture prevention in clinical practice.
Of Fractures & Drugs: Practical Issues in Osteoporosis Therapy
Mary Greeley Medical Center via YouTube
Overview
Syllabus
Intro
Disclosure
Meet the patient
Low trauma fractures and osteoporosis
Following a hip fracture...
The good news...
Where are we failing?
Proposed solutions What does not work
Proposed solutions What seems to work
Back to the patient
Effect of Denosumab on bone density
Denosumab VERSUS alendronate
Denosumab AFTER alendronate
Subtrochanteric fractures Definition
Can we stop bisphosphonates? FLEX trial
BMD: Stopping Denosumab
Bisphosphonates after Denosumab
The concept of consolidation therapy
Take home points
Taught by
Mary Greeley Medical Center
