Confounding in Biobanks: Challenges and Implications

Explore the complex issue of confounding in biobank research through this insightful 45-minute conference talk by Nancy Cox at the Computational Genomics Summer Institute (CGSI) 2023. Delve into the various ways confounding factors can infiltrate biobank studies, potentially skewing results and leading to misinterpretations. Examine key research papers, including Okbay et al.'s study on polygenic prediction of educational attainment, Yengo et al.'s work on genetic variants associated with human height, and Berg et al.'s investigation into reduced signals for polygenic adaptation of height in UK Biobank. Gain valuable insights into the challenges faced by researchers in genomics and biobank studies, and learn about potential strategies to identify and mitigate confounding effects in large-scale genetic analyses.