Dive into a comprehensive medical lecture on jaundice, exploring its definition and distinctions from related conditions like hyperbilirubinemia, icterus, and cholestasis. Examine the structure and types of hemoglobin, and understand the formation of hemosiderin, differentiating between hemosiderosis and hemochromatosis. Learn about the binding process of unconjugated bilirubin with bilirubin binding protein and its clinical implications. Investigate the conjugation of unconjugated bilirubin in the liver, its transport through the biliary canalicular system, and subsequent modifications in the gastrointestinal tract. Conclude by studying the reabsorption of urobilinogen into portal circulation, its fates, and clinical correlations, providing a thorough understanding of jaundice and related physiological processes.
Overview
Syllabus
Definition of jaundice and how it is different form hyperbilirubinemia, icterus and cholestasis? 0:01…min
Structure of hemoglobin and its types 18:22...min
Formation of hemosiderin and difference between hemosiderosis and hemochromatosis 22:11…min
Binding of unconjugated bilirubin with bilirubin binding protein and its clinical correlation 31:59...min
Conjugation of unconjugated bilirubin inside the liver and its clinical correlates 45:16…min
Transport of conjugated bilirubin through the biliary canalicular system into GIT 53:31…min
Modification of conjugated bilirubin in GIT 56:50…min
Reabsorption of Urobilinogen into portal circulation its fates and clinical correlations 59:14…min
Taught by
Dr. Najeeb Lectures
