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Explore a fresh approach to project initiation in this EuroPython 2019 conference talk. Learn how to prioritize business logic over traditional starting points like database design, migration systems, and user registration. Discover the benefits of clean architecture and its application in real-world scenarios. Gain practical insights into leveraging new Python features such as typings, mypy, and dataclasses in long-term production projects. Drawing from years of hands-on experience, this talk offers valuable knowledge beyond basic examples, focusing on real-life applications that stand the test of time in production environments.