Genetic Diversity in Cell Line Models and CRISPR Experimental Tools - Equity in Biomedicine

Explore the critical importance of genetic diversity in biomedical research through this 55-minute seminar from the Equity in Biomedicine Series. Delve into presentations by Broad Institute and MIT scientists as they discuss the need for increased genetic diversity in cell line models and CRISPR experimental tools. Learn how the lack of genetic diversity can limit scientific understanding and impact equity in downstream translational benefits. Discover why expanding the genetic diversity of pluripotent stem cell models is crucial for ensuring equitable and broadly useful scientific insights. Examine how genetic ancestry-based CRISPR guide bias can lead to false negatives in cell-based screens. Engage with the panel discussion moderated by Broad Institute scientist Anne Carpenter, focusing on challenges and opportunities in this vital area of biomedical research.