Challenges in Developing a Universal Metagenomic Diagnostic Test - 2024

Explore the challenges in developing a universal metagenomic diagnostic test in this 44-minute conference talk by Eleazar Eskin at the Computational Genomics Summer Institute (CGSI) 2024. Delve into the complexities of creating a comprehensive diagnostic tool that can detect multiple pathogens simultaneously using next-generation sequencing techniques. Learn about the innovative approaches to scaled-up testing for SARS-CoV-2 RNA through pooled and barcoded samples, as discussed in related research papers. Discover how lean principles can be applied to improve the quality and efficiency of high-throughput COVID-19 testing using SwabSeq, a barcoded sequencing-based platform. Gain insights into the evaluation of Swab-Seq as a scalable and sensitive assay for community surveillance of SARS-CoV-2 infection. Understand the potential applications and limitations of metagenomic diagnostic tests in the context of infectious disease detection and public health surveillance.