Dive into a comprehensive 55-minute lecture on receptor biology, exploring their types, structures, and locations. Learn about sensory receptors and their roles in physiology, biochemistry, and pharmacology. Understand the definition of receptors and their various locations within cells. Explore transmembrane receptors, with a focus on G-protein coupled receptors (GPCRs) and their mechanisms. Discover intracellular receptors, including cytosolic and nuclear types, as well as extracellular receptors like antithrombin III. Gain insights into the mechanism of action of heparin and its interaction with receptors. Conclude with a summary of key concepts and a preview of upcoming topics in receptor biology.
Overview
Syllabus
00:00 - What are we going to discuss in this lecture?
01:41 - Sensory receptors and receptors of physiology, biochemistry and pharmacology.
02:48 - What is a receptor?
12:51 - Where are the receptors located?
15:17 - transmembrane receptors and their types with examples.
21:04 - G-Protein receptors – a transmembrane type of receptor.
26:27 - Trimeric G proteins and monomeric G-proteins.
37:43 - Intracellular receptors cytosolic and nuclear receptors with examples.
44:47 - Extracellular receptors and their examples.
45:35 - Antithrombin III as an extracellular drug receptor. Heparin and it’s mechanism of action.
49:41 - . Review/Summary of this lecture.
53:30 - What we are going to discuss in the upcoming lecture?
Taught by
Dr. Najeeb Lectures
