AI in Structural Biology: Roots of Success

Explore the groundbreaking advancements in protein structure prediction using AI methods in this 57-minute talk by Dr. Helen Berman from USC Information Sciences Institute. Delve into the history of efforts to solve the protein folding problem, culminating in AlphaFold 2's successful prediction of protein structures in 2020. Discover the unique characteristics of training data derived from the Protein Data Bank and how this breakthrough opens new avenues for research in structural and cell biology. Gain insights from Dr. Berman's extensive experience in crystallography, structural biology, and her pivotal role in establishing and developing the Protein Data Bank archive. Learn about her ongoing work in using film and digital arts to communicate the importance of structural biology in medicine and health, including projects like the Target Zero documentary and the World in a Cell VR experience. Benefit from the expertise of this distinguished scientist, who is a member of the National Academy of Science, the American Academy for Arts and Sciences, and a recipient of numerous prestigious awards in the field of computational biosciences and structural biology.