Explore protein quality control mechanisms in this comprehensive lecture from the 9th MACS Colloquium at Kyoto University Graduate School of Science. Professor Kazutoshi Mori delves into fundamental concepts starting with cell biology basics, protein structure and function, and protein quality assessment. Learn about protein self-organization processes, endoplasmic reticulum stress response mechanisms, molecular chaperones and their evolutionary significance, and how disruptions in ER stress response lead to various pathological conditions. Through detailed explanations across seven key topics, gain deep insights into cellular protein management systems and their importance in maintaining cellular health.
Overview
Syllabus
- 細胞とは何か
- タンパク質とは何か
- タンパク質の品質
- タンパク質の自己組織化
- 小胞体ストレス応答
- 分子シャペロンと進化
- 小胞体ストレス応答、その破綻としての病態
Taught by
Kyoto-U OCW - Unofficial