Drug Design

The "Drug Design" course construction of the School of Pharmacy of Fudan University won the second prize of National Teaching Achievement, the first prize of Shanghai Teaching Achievement, the key course of Shanghai Education Commission (2011) and the Shanghai Excellent Course (2012).
The courses are based on the disciplines of life sciences, chemistry and bioinformatics, theoretical chemistry, organic chemistry, and medicinal chemistry related to drug discovery, and are set up 25 theoretical and 8 experimental knowledge points around the theoretical system of drug design, research strategies and methods, experimental principles and operations, and problem discussions, including: introduction, drug targets and their theories, structure-based drug design, lead compound property design optimization, computer-aided drug design experiments; Experimental courses include sequence alignment, protein structure demonstration, the construction and optimization of the three-dimensional structure of small molecules, the construction of small molecule pharmacophore models, and molecular docking, which will greatly help students apply pharmaceutical design to their own scientific research.