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The Next Frontier: Moving Beyond the Low LVEF Population
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Classroom Contents
Predicting and Preventing Sudden Cardiac Death in Patients Without Systolic Dysfunction
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- 1 Intro
- 2 Sudden Cardiac Death and Out-of-Hospital Cardiac Arrest
- 3 Racial and Sex Differences in Sudden Cardiac Death: The REGARDS Study
- 4 Lifetime Cumulative Incidence of SCD in ARIC by Race and Sex groups
- 5 Causes of Sudden Cardiac Death
- 6 Prospective Autopsy Characterization of Sudden Cardiac Death in San Francisco County: POST SCD Study
- 7 Mechanism of Sudden Cardiac Death
- 8 Proportion of EMS treated Cardiac Arrests with VF as Initial Rhythm in Seattle, USA
- 9 Treatment: Cardiopulmonary Resuscitation and Defibrillation
- 10 First Documented Cardiac Rhythm in Witnessed Arrests/ROC Epistry-Cardiac Arrest
- 11 Future Approaches to Resuscitation
- 12 Current Approach to SCD Prevention
- 13 Primary Prevention of SCD: ICD Trials
- 14 Wearable Defibrillator after Acute MI: The VEST Trial
- 15 LV Dysfunction and ICD Utilization after MI:Pre-SCD II Registry
- 16 Paradigm HF
- 17 LVEF and SCD Implications for Prevention and ICD Utilization
- 18 Estimating Myocardial Infarction Size With a Simple Electrocardiographic Marker Score
- 19 Arrhythmic Sudden Death Survival Prediction using Deep Learning Analysis of MRI SCAR in CHD
- 20 Biomarkers and SCD in the General Population
- 21 Replication of Biomarkers in the Population: Harvard SCD Consortium
- 22 Additive Value of Biomarkers on SCD Risk
- 23 Familial Aggregation of SCD
- 24 GWAS of Sudden Cardiac Arrest in General Population
- 25 Genetic Risk Scores and Sudden Cardiac Arrest: Mendelian Randomization
- 26 Rare Sequence Variation and SCD Exome Sequencing
- 27 Characteristics of SCD cases and controls
- 28 Filtration and Classification of Variants identified by Exome Sequencing
- 29 Pathogenic or Likely Pathogenic Variants in MESA Population
- 30 ECG Measures and SCD Risk General Population Studies
- 31 Absolute Incidence of SCD across High and Low Risk Populations
- 32 SCD Prevention in General Populations: Healthy Lifestyle and SCD
- 33 Sudden Death in HFPEF - TOPCAT Trial
- 34 PRE-DETERMINE Cohort Study (R01HL091069)SCD Risk Prediction in Patients without Severe Systolic Dysfunction
- 35 PREDETERMINE Baseline Characteristics
- 36 LVEF and Mode of Death in PRE-DETERMINE
- 37 Differential Association of Clinical Risk Factors With Sudden and/or Arrhythmic Death (SAD) vs. Competing Modes of Death
- 38 Age and Risk of Sudden and/or Arrhythmic Death (SAD) vs. Competing Modes of Death
- 39 Potential Impact of Absolute Risk on ICD Benefit: Number Needed to Treat (NNT) to Save One Life
- 40 Competing Risks and ICD Benefit: Proportional SAD Risk and Percent Mortality Reduction
- 41 DANISH TRIAL: IMPACT OF AGE ON COMPETING RISK
- 42 Importance of Competing Risk in Selecting Candidates for ICD Therapy
- 43 The ECG Stratifies SCD in Coronary Heart Disease Patients PREDETERMINE and ARTEMIS
- 44 Polygenic Risk Score (PRS) for CAD Specifically Predicts SAD in PREDETERMINE
- 45 Polygenic Risk Score (PRS): Additive SAD Risk Prediction to Clinical Factors and ECG
- 46 Summary: Challenges to Reducing Mortality from Sudden Cardiac Death
- 47 The Next Frontier: Moving Beyond the Low LVEF Population
