Predicting and Preventing Sudden Cardiac Death in Patients Without Systolic Dysfunction

Predicting and Preventing Sudden Cardiac Death in Patients Without Systolic Dysfunction

Cardiology University of Washington via YouTube Direct link

Additive Value of Biomarkers on SCD Risk

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22 of 47

Additive Value of Biomarkers on SCD Risk

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Predicting and Preventing Sudden Cardiac Death in Patients Without Systolic Dysfunction

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  1. 1 Intro
  2. 2 Sudden Cardiac Death and Out-of-Hospital Cardiac Arrest
  3. 3 Racial and Sex Differences in Sudden Cardiac Death: The REGARDS Study
  4. 4 Lifetime Cumulative Incidence of SCD in ARIC by Race and Sex groups
  5. 5 Causes of Sudden Cardiac Death
  6. 6 Prospective Autopsy Characterization of Sudden Cardiac Death in San Francisco County: POST SCD Study
  7. 7 Mechanism of Sudden Cardiac Death
  8. 8 Proportion of EMS treated Cardiac Arrests with VF as Initial Rhythm in Seattle, USA
  9. 9 Treatment: Cardiopulmonary Resuscitation and Defibrillation
  10. 10 First Documented Cardiac Rhythm in Witnessed Arrests/ROC Epistry-Cardiac Arrest
  11. 11 Future Approaches to Resuscitation
  12. 12 Current Approach to SCD Prevention
  13. 13 Primary Prevention of SCD: ICD Trials
  14. 14 Wearable Defibrillator after Acute MI: The VEST Trial
  15. 15 LV Dysfunction and ICD Utilization after MI:Pre-SCD II Registry
  16. 16 Paradigm HF
  17. 17 LVEF and SCD Implications for Prevention and ICD Utilization
  18. 18 Estimating Myocardial Infarction Size With a Simple Electrocardiographic Marker Score
  19. 19 Arrhythmic Sudden Death Survival Prediction using Deep Learning Analysis of MRI SCAR in CHD
  20. 20 Biomarkers and SCD in the General Population
  21. 21 Replication of Biomarkers in the Population: Harvard SCD Consortium
  22. 22 Additive Value of Biomarkers on SCD Risk
  23. 23 Familial Aggregation of SCD
  24. 24 GWAS of Sudden Cardiac Arrest in General Population
  25. 25 Genetic Risk Scores and Sudden Cardiac Arrest: Mendelian Randomization
  26. 26 Rare Sequence Variation and SCD Exome Sequencing
  27. 27 Characteristics of SCD cases and controls
  28. 28 Filtration and Classification of Variants identified by Exome Sequencing
  29. 29 Pathogenic or Likely Pathogenic Variants in MESA Population
  30. 30 ECG Measures and SCD Risk General Population Studies
  31. 31 Absolute Incidence of SCD across High and Low Risk Populations
  32. 32 SCD Prevention in General Populations: Healthy Lifestyle and SCD
  33. 33 Sudden Death in HFPEF - TOPCAT Trial
  34. 34 PRE-DETERMINE Cohort Study (R01HL091069)SCD Risk Prediction in Patients without Severe Systolic Dysfunction
  35. 35 PREDETERMINE Baseline Characteristics
  36. 36 LVEF and Mode of Death in PRE-DETERMINE
  37. 37 Differential Association of Clinical Risk Factors With Sudden and/or Arrhythmic Death (SAD) vs. Competing Modes of Death
  38. 38 Age and Risk of Sudden and/or Arrhythmic Death (SAD) vs. Competing Modes of Death
  39. 39 Potential Impact of Absolute Risk on ICD Benefit: Number Needed to Treat (NNT) to Save One Life
  40. 40 Competing Risks and ICD Benefit: Proportional SAD Risk and Percent Mortality Reduction
  41. 41 DANISH TRIAL: IMPACT OF AGE ON COMPETING RISK
  42. 42 Importance of Competing Risk in Selecting Candidates for ICD Therapy
  43. 43 The ECG Stratifies SCD in Coronary Heart Disease Patients PREDETERMINE and ARTEMIS
  44. 44 Polygenic Risk Score (PRS) for CAD Specifically Predicts SAD in PREDETERMINE
  45. 45 Polygenic Risk Score (PRS): Additive SAD Risk Prediction to Clinical Factors and ECG
  46. 46 Summary: Challenges to Reducing Mortality from Sudden Cardiac Death
  47. 47 The Next Frontier: Moving Beyond the Low LVEF Population

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