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Prioritize druggable genes for phenotypes of interest
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Classroom Contents
Individual-level Tissue-Specific Imputed Transcriptomes in Drug Target Prioritization and Disease Risk Prediction
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- 1 Intro
- 2 Introduction and Background
- 3 Trait-relevant tissues and transcriptome imputation
- 4 Prioritize druggable genes for phenotypes of interest
- 5 Joint analysis of TWAS and co-localization
- 6 Gene expression-based risk prediction
- 7 Analysis overview
- 8 Polygenic Risk Score
- 9 Risk discrimination and group stratification
- 10 Phenome-wide scans for established drug targets
- 11 Take-home message
