High-throughput Diagnostics and Sequencing at the Pandemic Response Lab NYC

High-throughput Diagnostics and Sequencing at the Pandemic Response Lab NYC

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CoV2 assay targets

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4 of 33

CoV2 assay targets

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High-throughput Diagnostics and Sequencing at the Pandemic Response Lab NYC

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  1. 1 Intro
  2. 2 The CoV2 test principle is straightforward How do we make it high throughput?
  3. 3 CoV2 test steps
  4. 4 CoV2 assay targets
  5. 5 CoV2 assay details
  6. 6 Test development timeline
  7. 7 Virus inactivation
  8. 8 RNA extraction
  9. 9 Sample processing pipeline - throughput
  10. 10 Equipment stoichiometry - one 'line' PRL NYC has three lines operating
  11. 11 Sample tracking and analysis - DaViD
  12. 12 Future of sample tracking
  13. 13 DaViD-analysis interface
  14. 14 Test statistics
  15. 15 Current optimization work
  16. 16 Changing sample collection paradigm
  17. 17 Pooled testing
  18. 18 At-home saliva collection
  19. 19 What's next for PRL testing?
  20. 20 CoV2 whole genome sequencing
  21. 21 Sequencing pipeline is integrated into the testing line
  22. 22 Sequencing pipeline overview
  23. 23 Sequencing development timeline
  24. 24 GISAID submissions by state
  25. 25 Variant growth over time
  26. 26 NYC variant sequences from PRL
  27. 27 NYC variant distributions from PRL
  28. 28 NYC variant distributions - B.1.1.7
  29. 29 NYC variant distributions - B.1.526 +E484K
  30. 30 PRL testing vs sequencing distribution
  31. 31 Executive team
  32. 32 Scientific Advisory Board
  33. 33 The team that does it all

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