On the Number of Genealogical Ancestors Tracing to Source Groups in Admixed Populations

On the Number of Genealogical Ancestors Tracing to Source Groups in Admixed Populations

Computational Genomics Summer Institute CGSI via YouTube Direct link

ancestry occurs during the initial epoch

16 of 19

16 of 19

ancestry occurs during the initial epoch

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On the Number of Genealogical Ancestors Tracing to Source Groups in Admixed Populations

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  1. 1 Intro
  2. 2 Overview
  3. 3 Only some of your genealogical ancestors will be your genetic ancestors
  4. 4 Admixed populations are a combination of multiple sources
  5. 5 Individual genomes carry signatures of admixture
  6. 6 Classically admixture has been modelled by considering simpler scenarios
  7. 7 Implement a mechanistic model of admixture
  8. 8 Use ancestry proportions from the present to estimate, Z, the number of ancestors from each source population that contributed to genome of an admixed individual
  9. 9 Implementing the model to improve our understanding of African American history
  10. 10 Summary of our approach for fitting the model
  11. 11 Model assumptions
  12. 12 Estimating the number of genealogical ancestors. that are represented in an African American individual's genome
  13. 13 Estimating the number of genealogical ancestors that are represented in an African American individual's genome
  14. 14 Hundreds of African ancestors and tens of European ancestors
  15. 15 As the number of African ancestors increases the number of European ancestors decreases
  16. 16 ancestry occurs during the initial epoch
  17. 17 Number of African and European ancestors varies per generation
  18. 18 The probability of having an African or European ancestor peaks during the height of the Trans- Atlantic Slave Trade
  19. 19 Global ancestry can be used to infer the admixture history of admixed individuals

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