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On the Number of Genealogical Ancestors Tracing to Source Groups in Admixed Populations
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- 1 Intro
- 2 Overview
- 3 Only some of your genealogical ancestors will be your genetic ancestors
- 4 Admixed populations are a combination of multiple sources
- 5 Individual genomes carry signatures of admixture
- 6 Classically admixture has been modelled by considering simpler scenarios
- 7 Implement a mechanistic model of admixture
- 8 Use ancestry proportions from the present to estimate, Z, the number of ancestors from each source population that contributed to genome of an admixed individual
- 9 Implementing the model to improve our understanding of African American history
- 10 Summary of our approach for fitting the model
- 11 Model assumptions
- 12 Estimating the number of genealogical ancestors. that are represented in an African American individual's genome
- 13 Estimating the number of genealogical ancestors that are represented in an African American individual's genome
- 14 Hundreds of African ancestors and tens of European ancestors
- 15 As the number of African ancestors increases the number of European ancestors decreases
- 16 ancestry occurs during the initial epoch
- 17 Number of African and European ancestors varies per generation
- 18 The probability of having an African or European ancestor peaks during the height of the Trans- Atlantic Slave Trade
- 19 Global ancestry can be used to infer the admixture history of admixed individuals
