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FIRST DESCRIPTION OF THERAPEUTIC DRUG MONITORING
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Introduction to Clinical Pharmacology and Therapeutics - Pharmacokinetic Concepts - Part 2
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- 1 Clinical Pharmacology
- 2 Pharmacokinetics - Pharmacodynamics
- 3 USES OF PHARMACOKINETICS
- 4 Dose-Response Relationship
- 5 "Target concentration" strategy
- 6 FIRST DESCRIPTION OF THERAPEUTIC DRUG MONITORING
- 7 DRUG CANDIDATES FOR TDM
- 8 TARGET CONCENTRATION STRATEGY
- 9 TRADITIONAL Guidelines for DIGOXIN Levels
- 10 SURVIVAL as a function of DIGOXIN LEVEL measured after 1 Month Rx
- 11 3 DISTRIBUTION VOLUMES
- 12 INITIAL DIGITALIZATION
- 13 DISTRIBUTION DELAYS ONSET of DIGOXIN Chronotropic Action
- 14 ELIMINATION HALF-LIFE
- 15 ELIMINATION PARAMETERS
- 16 MAINTENANCE DIGOXIN THERAPY
- 17 CUMULATION FACTOR
- 18 ELIMINATION RATE CONSTANT
- 19 LOADING & MAINTENANCE DOSES
- 20 CREATININE CLEARANCE EQUATION
- 21 MDRD Study Equation
- 22 CKD-EPI Collaboration Equation
- 23 STEADY STATE CONCENTRATION
- 24 PHENYTOIN KINETICS in Normal Subjects
- 25 STEADY STATE EQUATIONS
- 26 RELATIONSHIP OF PLASMA LEVEL TO PHENYTOIN DOSE
- 27 PATIENT WHO BECAME TOXIC ON A PHENYTOIN DOSE OF 300 mg/day
- 28 BASIS OF APPARENT FIRST-ORDER KINETICS