Introduction to Clinical Pharmacology and Therapeutics - Pharmacokinetic Concepts - Part 2

Introduction to Clinical Pharmacology and Therapeutics - Pharmacokinetic Concepts - Part 2

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Clinical Pharmacology

1 of 28

1 of 28

Clinical Pharmacology

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Introduction to Clinical Pharmacology and Therapeutics - Pharmacokinetic Concepts - Part 2

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  1. 1 Clinical Pharmacology
  2. 2 Pharmacokinetics - Pharmacodynamics
  3. 3 USES OF PHARMACOKINETICS
  4. 4 Dose-Response Relationship
  5. 5 "Target concentration" strategy
  6. 6 FIRST DESCRIPTION OF THERAPEUTIC DRUG MONITORING
  7. 7 DRUG CANDIDATES FOR TDM
  8. 8 TARGET CONCENTRATION STRATEGY
  9. 9 TRADITIONAL Guidelines for DIGOXIN Levels
  10. 10 SURVIVAL as a function of DIGOXIN LEVEL measured after 1 Month Rx
  11. 11 3 DISTRIBUTION VOLUMES
  12. 12 INITIAL DIGITALIZATION
  13. 13 DISTRIBUTION DELAYS ONSET of DIGOXIN Chronotropic Action
  14. 14 ELIMINATION HALF-LIFE
  15. 15 ELIMINATION PARAMETERS
  16. 16 MAINTENANCE DIGOXIN THERAPY
  17. 17 CUMULATION FACTOR
  18. 18 ELIMINATION RATE CONSTANT
  19. 19 LOADING & MAINTENANCE DOSES
  20. 20 CREATININE CLEARANCE EQUATION
  21. 21 MDRD Study Equation
  22. 22 CKD-EPI Collaboration Equation
  23. 23 STEADY STATE CONCENTRATION
  24. 24 PHENYTOIN KINETICS in Normal Subjects
  25. 25 STEADY STATE EQUATIONS
  26. 26 RELATIONSHIP OF PLASMA LEVEL TO PHENYTOIN DOSE
  27. 27 PATIENT WHO BECAME TOXIC ON A PHENYTOIN DOSE OF 300 mg/day
  28. 28 BASIS OF APPARENT FIRST-ORDER KINETICS

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