A Nuclear Localization Signal Targets Tail-Anchored Membrane Proteins to the Inner Nuclear Envelope in Plants

A Nuclear Localization Signal Targets Tail-Anchored Membrane Proteins to the Inner Nuclear Envelope in Plants

Society for Experimental Biology via YouTube Direct link

Soluble proteins are actively imported into the nucleus, through binding of the NLS

2 of 13

2 of 13

Soluble proteins are actively imported into the nucleus, through binding of the NLS

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A Nuclear Localization Signal Targets Tail-Anchored Membrane Proteins to the Inner Nuclear Envelope in Plants

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  1. 1 Intro
  2. 2 Soluble proteins are actively imported into the nucleus, through binding of the NLS
  3. 3 How do proteins traffic to the Inner Nuclear Membrane?
  4. 4 Models for membrane protein transport to the INM
  5. 5 Transport-Factor Mediated Trafficking of inner nuclear membrane proteins
  6. 6 Experimental Questions
  7. 7 Targeting a tail anchored ER protein to the nuclear envelope
  8. 8 Measuring NE enrichment using nuclear localization index NLI
  9. 9 Addition of an NLS to an chimeric membrane protein results in NE enrichment
  10. 10 Defining Rules for NE Targeting
  11. 11 NLS fused chimeric membrane proteins access
  12. 12 Working model of NLS-mediated INM protein trafficking
  13. 13 Addition of a monopartite NLS is sufficient to enrich an artificial membrane protein at the NE

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