Improving Outcomes - Lessons Learned from Pediatric Sepsis

Improving Outcomes - Lessons Learned from Pediatric Sepsis

OPENPediatrics via YouTube Direct link

General Principles

2 of 17

2 of 17

General Principles

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Improving Outcomes - Lessons Learned from Pediatric Sepsis

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  1. 1 Intro
  2. 2 General Principles
  3. 3 Epidemiologic Burden of Sepsis in Children
  4. 4 Categorization of Shock • Hypovolemic shock
  5. 5 Physiologic Basis for Shock
  6. 6 Role of Early Fluid Resuscitation in Pediatric Septic Shock
  7. 7 The Iterative Cycle of Discovery
  8. 8 Hemodynamics of Pediatric Sepsis
  9. 9 Case Study - After Stabilization
  10. 10 Drivers of improvement
  11. 11 Traditional Methodology - Whole Blood Assay
  12. 12 Attenuated Gene Expression vs. Immune Cell Dysfunction
  13. 13 Mechanisms Affecting Gene Expression
  14. 14 Post-Translational Histone Modifications
  15. 15 Activation of Gene-Off Signature
  16. 16 Integrated Microfluidic Chip for Functional Response
  17. 17 Localized Surface Plasmon Resonance (LSPR) Imaging

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