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Intro
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Improving Outcomes - Lessons Learned from Pediatric Sepsis
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- 1 Intro
- 2 General Principles
- 3 Epidemiologic Burden of Sepsis in Children
- 4 Categorization of Shock • Hypovolemic shock
- 5 Physiologic Basis for Shock
- 6 Role of Early Fluid Resuscitation in Pediatric Septic Shock
- 7 The Iterative Cycle of Discovery
- 8 Hemodynamics of Pediatric Sepsis
- 9 Case Study - After Stabilization
- 10 Drivers of improvement
- 11 Traditional Methodology - Whole Blood Assay
- 12 Attenuated Gene Expression vs. Immune Cell Dysfunction
- 13 Mechanisms Affecting Gene Expression
- 14 Post-Translational Histone Modifications
- 15 Activation of Gene-Off Signature
- 16 Integrated Microfluidic Chip for Functional Response
- 17 Localized Surface Plasmon Resonance (LSPR) Imaging
