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Gene duplication and the adaptive evolution of a classic genetic switch
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How Do Cells of Saccharomyces Cerevisiae Behave in a Medium Containing Repressing and Including Carbon Sources
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- 1 How do cells of Saccharomyces cerevisiae behave in a medium containing repressing and including carbon sources
- 2 Erwin Schrodinger 1944
- 3 How do cells of budding yeast behave in a medium containing repressing and inducing carbon sources?
- 4 Diauxie in Bacteria
- 5 Revisiting Diauxie in yeast
- 6 Galactose Catabolism
- 7 Evolution of GAL Genetic Switch in Yeast
- 8 S.cerevisiae GAL switch
- 9 Paradox 1: Long term adaptation
- 10 Paradox 2: Unusual Epistatic interactions in the GAL switch
- 11 "How wounderful that we have met with a paradox, Now we have some hope of making progress"
- 12 Biochemistry or Biochemist? is at odds with Genetics!
- 13 Biochemical data is clearly incompatible with the genetic data
- 14 Gal3p physically interacts with Gal80s-1p
- 15 GAL genetic switch of k.lactis Vs S.cerevisiae
- 16 Would GAL80s-1 GAL4c strain show long term adaptation?
- 17 Ultra-sensitivity of the GAL switch
- 18 Glucose repression is reduced in the mutant strain
- 19 Polygenic evolution of a sugar specialization trade-off in yeast
- 20 Polymorhisms in the yeast galactose sensor underlie a natural contium of nutrient-decision phenotypes
- 21 Diauxie variation is due to polymorphism at GAL3 locus
- 22 Growth on Glucose 0.25% + Galactose 0.25%
- 23 Growth on Melibiose-A disaccharide of Glu and Gal
- 24 Competition between the mutant and wild type
- 25 Gene duplication and the adaptive evolution of a classic genetic switch
- 26 A living vector field reveals constraints on galactose network induction in yeast