Diffusion Probabilistic Modeling of Protein Backbones in 3D for Motif-Scaffolding

Diffusion Probabilistic Modeling of Protein Backbones in 3D for Motif-Scaffolding

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- Intro

1 of 13

1 of 13

- Intro

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Diffusion Probabilistic Modeling of Protein Backbones in 3D for Motif-Scaffolding

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  1. 1 - Intro
  2. 2 - Computational protein design workflow
  3. 3 - Diffusion models on protein backbones
  4. 4 - Forward diffusion and reverse denoising
  5. 5 - Why do diffusion models work?
  6. 6 - Why do diffusion for proteins?
  7. 7 - Model details
  8. 8 - Unconditional sampling
  9. 9 - Model limitations and failure modes
  10. 10 - Sampling SMCDiff
  11. 11 - Motif-scaffolding case studies and failure case
  12. 12 - Related work and conclusion
  13. 13 - Q+A

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