Detecting Viruses with CRISPR: Applications and Technologies

Detecting Viruses with CRISPR: Applications and Technologies

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Acknowledgements

23 of 24

23 of 24

Acknowledgements

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Detecting Viruses with CRISPR: Applications and Technologies

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  1. 1 Intro
  2. 2 Where do we want to detect viruses?
  3. 3 CRISPR allows bacteria to defend themselves against phages
  4. 4 Cas13 is the RNA-targeting equivalent of Cas9
  5. 5 Cas13 has similar potential to Cas9 but for RNA
  6. 6 Using Cas13 to detect nucleic acids
  7. 7 SHERLOCK uses Cas13 for sensitive nucleic acid detection
  8. 8 SHERLOCK can work at the point of care
  9. 9 SHINE V1 (Streamlined Highlighting of Infections to Navigate Epidemics)
  10. 10 SHINE v2: towards at-home COVID-19 testing
  11. 11 SHINE v2 outperforms rapid antigen tests
  12. 12 SHINE v2 can be incubated using body heat
  13. 13 Can we scale up SHERLOCK?
  14. 14 CARMEN - SHERLOCK at massive multiplex
  15. 15 Microfluidic CARMEN (mCARMEN)
  16. 16 Developing a CARMEN respiratory virus panel (RVP)
  17. 17 Streamlining the workflow of CARMEN-RVP
  18. 18 CARMEN-RVP has exquisite analytical sensitivity
  19. 19 The CARMEN Variant Identification Panel (VIP)
  20. 20 SARS-CoV-2 lineage identification with the VIP
  21. 21 Omicron produces a unique signature on the VIP
  22. 22 Tracking the spread of Omicron in Massachussetts
  23. 23 Acknowledgements
  24. 24 We are recruiting postdocs!

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