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Clinical Application
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Classroom Contents
Clinical Validation of Whole Genome Methylation Profiling Classifier for Central Nervous System Tumors
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- 1 Introduction
- 2 Disclosures
- 3 Sample Workflow
- 4 methylation data
- 5 normalization
- 6 beta value
- 7 classification
- 8 training data
- 9 feature selection
- 10 training classifier
- 11 dimensionality reduction
- 12 results
- 13 concordant data
- 14 validation
- 15 correlation
- 16 interference
- 17 Typical case
- 18 Disney Plot
- 19 Copy Number Plot
- 20 Discussion
- 21 Conclusions
- 22 Acknowledgements
- 23 Questions
- 24 Clinical Laboratory
- 25 Sharing the Classifier
- 26 Clinical Application
- 27 Constitutional Disorders
- 28 Additional Questions
- 29 Probability Score Recalibration
- 30 Can Pathologists Determine Classification of a Sample
