Clinical Validation of Whole Genome Methylation Profiling Classifier for Central Nervous System Tumors

Clinical Validation of Whole Genome Methylation Profiling Classifier for Central Nervous System Tumors

Cancer Genomics Consortium via YouTube Direct link

results

12 of 30

12 of 30

results

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Clinical Validation of Whole Genome Methylation Profiling Classifier for Central Nervous System Tumors

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  1. 1 Introduction
  2. 2 Disclosures
  3. 3 Sample Workflow
  4. 4 methylation data
  5. 5 normalization
  6. 6 beta value
  7. 7 classification
  8. 8 training data
  9. 9 feature selection
  10. 10 training classifier
  11. 11 dimensionality reduction
  12. 12 results
  13. 13 concordant data
  14. 14 validation
  15. 15 correlation
  16. 16 interference
  17. 17 Typical case
  18. 18 Disney Plot
  19. 19 Copy Number Plot
  20. 20 Discussion
  21. 21 Conclusions
  22. 22 Acknowledgements
  23. 23 Questions
  24. 24 Clinical Laboratory
  25. 25 Sharing the Classifier
  26. 26 Clinical Application
  27. 27 Constitutional Disorders
  28. 28 Additional Questions
  29. 29 Probability Score Recalibration
  30. 30 Can Pathologists Determine Classification of a Sample

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